peroxynitrite相关论文
Nitrosative stress in human spermatozoa causes cell death characterized by induction of mitochondria
Peroxynitrite is a highly reactive nitrogen species and a potent inducer of apoptosis and necrosis in somatic cells.Pero......
Reaction mechanisms of peroxynitrite with amino acids are the bases to explore the damage of protein induced by peroxyni......
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Anti-peroxynitrite Treatment Ameliorate Vasorelaxation of Resistance Arteries in Aging Rats:Involvem
Numerous studies have found that age-associated structural and functional alterations in arteries were characterized by ......
Nitration of Thioredoxin Reductase Increased Susceptibility to Myocardial Ischemia/Reperfusion Injur
The age-related loss of antioxidant defense reduces the recovery from myocardial ischemia/reperfusion injury (MI/R) in a......
Design of a Long-wavelength Fluorescent Probe for Tracking of Peroxynitrite in Live Cells and Inflam
Peroxynitrite(OONO-),as a reactive oxygen species(ROS) in organisms,is produced by the rapid reaction between nitric oxi......
Inflammation imaging and investigation of drug-induced hepatotoxicity with reaction based fluorescen
Peroxynitrite(ONOO-)is a kind of reactive oxygen species(ROS)with super activity of oxidization and nitration,and overpr......
Selenoprotein R protects human lens epithelial cells against peroxynitrite-induced apoptosis and F-a
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已证实体内过氧亚硝酸根离子与人体多种病理反应相关。采用S-亚硝基硫醇为一氧化氮供体化合物、水溶性优于核黄素的聚乙二醇化核黄......
Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithi
Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite r......
Identification and quantification of flavonoids in Carica papaya leaf and peroxynitrite-scavenging a
Objective: To characterize the types, contents, and peroxynitrite-scavenging activities of flavonoids in the leaf of Car......
目的 该实验旨在研究过氧化亚硝酸对心脏停跳大鼠肝细胞凋亡的影响.方法 切取雄性Wistar大鼠肝脏后,通过门静脉插管灌注60 ml 4℃H......
目的探究过氧亚硝酸盐(peroxynitrite,ONOO-)诱导人中枢血管平滑肌细胞(HCVSMCs)凋亡过程中盘状结构域受体(DDR2)基因表达的变化。......
开发了两种水溶性的反应型氟硼二吡咯(BODIPY)荧光探针Ac-Phe-BODIPY和Ac-BODIPY,并将其用于活性氧物种(ROS)和活性氮物种(RNS)中......
,Diverse Effects of L-arginine on Cardiac Function of Rats Subjected to Myocardial Ischemia and Repe
In vivo administration of L-arginine at different time points during the course of myocardial ischemia and reperfusion (......
Superoxide anion and NO can react to form the highly oxidizing species peroxynitrite(ONOO-)which can react directly with......
多发性硬化(MS)是一种T细胞介导的自身免疫性疾病,其确切病因及发病机制尚不清楚,免疫学因素在发病中起着关键作用,其中在免疫细胞......
本文通过对荣华二采区10...
Peroxynitrite(ONOO) is a powerful oxidant and nitrosative agent and has in vivo existence.The half life of ONOO at physi......
Although cholecystokinin octapeptide-8 is important for neurological function, its neuropro-tective properties remain un......
AIM: Peroxynitrite (ONOO-) is a powerful oxidant shown to damage membranes. In the present study, the effect of taurine ......
The peroxynitrite/porphyrin biomimetic system was established to investigate the effects of peroxynitrite on benzo[a]pyr......
在培养的牛肺动脉内皮细胞(bovine pulmonary artery endothelial cells, BPAECs)水平上, 观察脂多糖( lipopolysaccharide, LPS)......
以亚甲蓝和苯甲酸为羟自由基捕获剂,用分光光度法研究了过亚硝酸根分解反应的机制。研究发现过亚硝酸根在生理pH下分解时有羟自由基与......
实验用离体血管环张力测定技术,观察过氧亚硝基阴离子(ONOO-)对离体预收缩的兔肺动脉的舒张反应、肺动脉内皮细胞对舒张反应的影响......
AIM: Peroxynitrite (ONOO-) is a powerful oxidant shown to damage membranes. In the present study, the effect of taurine ......
探讨丹皮酚(Pae)拮抗过氧亚硝基阴离子(ONOO-)对体外培养大鼠成骨细胞分化的影响.用改良的组织块法分离培养新生大鼠颅骨成骨细胞,......
基于血红蛋白催化过氧亚硝酸根阴离子(ONOO-)氧化L-酪氨酸的反应,建立了一种测定ONOO-的新方法.在优化实验条件下,酪氨酸荧光强度随O......
内皮祖细胞(Endothelial Progenitor Cells,EPCs)是成熟内皮细胞的前体细胞,它同时表达干细胞和内皮细胞的相关抗原,具有增殖、迁移、分......
目的:通过检测MT对ONOO-、NO、的影响,探讨MT对过氧亚硝基反应体系的调控作用。方法: 采用多种化学发光体系在体外检测。结果:MT对ONOO......
目的:探讨牛肺动脉内皮细胞(BPAEC)产生过氧亚硝基阴离子(ONOO^-)的能力及其作用。方法:用流式细胞免疫荧光技术,定量检测内毒素主要成分......
目的探讨丹皮酚拮抗过氧亚硝基阴离子(ONOO^-)对体外培养大鼠成骨细胞凋亡的作用.方法用改良的组织块法分离培养新生大鼠颅骨成骨细......
本文探讨过氧亚硝基阴离子(ONOO-)在内毒素致肺血管损伤中的介导作用和八肽胆囊收缩素(CCK)的保护作用及其机制。结果发现,内毒素主......
探讨过氧亚硝基阴离子(peroxynitrite, ONOO-)对离体兔肺动脉反应性变化的影响.用离体血管环技术观察ONOO-孵育后肺动脉对钙离子载......
目的探讨过氧亚硝酸根(peroxynitrite,ONOO-)和重组人碱性成纤维细胞生长因子(recombinant human basic fibroblast growth factor,b ......
糖尿病氧化应激生成的超氧阴离子与内皮细胞生成的一氧化氮反应生成过氧化亚硝基阴离子,通过硝基化作用修饰多种蛋白的酪氨酸残基,......
目的研究羟基红花黄色素A(HSYA)对体外ON00途径和亚铁血红素/亚硝酸钠/过氧化氢(heme/NaNO2/H202)途径引起脑组织蛋白质羰基化的影响。方法......
目的通过制备小鼠机械性创伤模型,观察过氧亚硝基(ONOO-)在机械性创伤致心肌细胞凋亡中的作用和机制。方法利用Noble-Collip创伤仪制......
目的心肌缺血/再灌注早期给予L-精氨酸,观察其对心脏的保护作用。方法雄性Wistar大鼠45只,随机分为3组(n=15):伪手术组(Sham组),缺血/再灌注+......
肠屏障功能是肠道的一个重要特征,可以保护宿主不受外来抗原的干扰和入侵,它由一系列特异性和非特异性防御机制组成,包括肠管的蠕动、......
利用紫外-可见分光光度计在乙醇介质中研究了合成的4种对位取代四苯基钴卟啉对过亚硝酸根分解的催化作用.首次发现钴卟啉可以催化ON......
用分子轨道对称生规则阐明生物体系NO与O^-2、NO2、OH、LOO反应动力主其生物学意义。从分子轨道,电子结构,化学键的稳定性,诱导效应以及极化与反极化......
目的 观察过氧亚硝酸盐对糖尿病大鼠胸主动脉血管收缩功能的影响.方法 雄性SD大鼠30只,大鼠随机分为3组:对照组、糖尿病组和糖尿病+......
该文以2-(2′-羟基-3′-醛基-5′-甲基苯基)苯并噻唑和1,1-二甲基肼为原料,通过一步缩合,简单过滤处理得到一种基于苯并噻唑的新型......
0引言过亚硝酸根(ONOO^-)是活性很高的生物小分子,在体内可损伤酪氨酸、色氨酸、半胱氨酸等多种氨基酸,产生多种损伤产物。其中过亚硝......
系统介绍了ONOO^-活性氧的化学性质,并对其参与的主要化学反应进行了分类和总结.同时,比较了近年来用于ONOO^-检测的方法,并重点论述了......
对过氧亚硝酸的细胞生物学效应做了简单阐述,全面回顾和总结了近年来用于过氧亚硝酸测定的各种分析方法,并对各种方法的优缺点及其适......
建立柱后HPLC-DAD-(Luminol-ONOO^-)-CL(方法1)和柱前ONOO^--HPLC-DAD(方法2)两种简单、快速在线检测清除ON00^-的方法,将这两种方法应用......
目的探讨过氧亚硝酸盐(ONOO-)诱导人脑血管平滑肌细胞(HCVSMCs)凋亡过程中PDCD4基因表达的变化。方法以体外培养的HCVSMCs系为实验材料......
AIM: Experimental studies suggest that free radicals are involved in acid and pepsin-induced damage of esophageal mucosa......